English Chinese Russian German French Japanese Portuguese Hindi Telugu Tamil

Anales de investigación clínica y de laboratorio

  • ISSN: 2386-5180
  • Índice h de la revista: 17
  • Puntuación de cita de revista: 6.26
  • Factor de impacto de la revista: 5.31
Indexado en
  • Genamics JournalSeek
  • Infraestructura Nacional de Conocimiento de China (CNKI)
  • CiteFactor
  • Directorio de indexación de revistas de investigación (DRJI)
  • Publón
  • pub europeo
  • Google Académico
  • SHERPA ROMEO
  • Laboratorios secretos de motores de búsqueda
Ver más
Comparte esta página

Abstracto

Gene Polymorphism of Superoxide Dismutase in Gestational Diabetes Mellitus in Pregnant Women

Mai M. Madkour1*, Abd El-Aziz F. Abd El-Aziz1, Fardous F. El-Senduny1, Afaf M. Elsaid2 and Abd ElAziz A. El-Refa

Background: Gestational diabetes mellitus is the most common metabolic disorder that develops during pregnancy. GDM can cause major health problems for the mother both during pregnancy and after the baby is born. In addition, the metabolism of the mother's kids is abnormal. The study aimed to investigate superoxide dismutase 1 genetic variants in pregnant women diagnosed with gestational diabetes using amplification refractory mutation system analysis.

Results: Our study demonstrated that the frequencies of genotypes in women with GDM were SOD1-AG (90.0%). The study revealed there is a significant difference in the frequency of the genotype of SOD1 between GDM and healthy pregnant women.

Conclusions: To the best of our knowledge, this is the first study to indicate that the genotype of SOD1 (A/G rs2070424) has a significant impact on the development of gestational diabetes mellitus in Egyptian women.